Research Opportunity Number: CHE-02

Project Title: Novel Proteins with Novel Functions

Project Summary: All living systems on earth are sustained by genes encoding proteins capable of performing the essential functions of biology. Because of the evolutionary relatedness of all living systems on earth, many sequences are shared from one organism to another. Are the genes and proteins observed in nature the only ones capable of sustaining life? Alternatively, might it be possible to design genes and proteins that never existed in nature, but nonetheless have the ability to sustain the growth of living organisms? The research in our laboratory aims to answer these questions by designing and constructing large collections of novel genes that encode artificial proteins. We then test the activities of these proteins in vitro and probe their functionality in living cells.

Student Roles and Responsibilities: The student will do research in the lab. The student will be guided by a senior graduate student in the laboratory..

Additional Considerations: Requirements are enthusiasm for experimental science and basic courses in chemistry and biology. The time requirement is flexible and will be discussed with individual applicants.

Department/Institute: Chemistry

Faculty Sponsor: Michael Hecht

Participation Dates: 6/20/2024 to 8/31/2024

Stipend Offered: $0

Number of Internships Available: 0-1

Application Deadline: March 15, 2024, midnight eastern daylight time